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Networks of genes regulated upon silencing of DSCAM-AS1 in HEC-1B and RL95-2 cells as assessed <t>by</t> <t>Affymetrix</t> <t>GeneChip</t> and subsequent pathway analyses using Ingenuity Pathway Analysis (IPA) software (Qiagen Bioinformatics). Knockdown was less efficient in RL95-2 cells due to its positive ERα status (see Discussion section). The gene networks of upregulated genes (red) and downregulated genes (green) also indicate their key upstream regulators (yellow). Solid arrows: affecting gene expression.
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Networks of genes regulated upon silencing of DSCAM-AS1 in HEC-1B and RL95-2 cells as assessed by Affymetrix GeneChip and subsequent pathway analyses using Ingenuity Pathway Analysis (IPA) software (Qiagen Bioinformatics). Knockdown was less efficient in RL95-2 cells due to its positive ERα status (see Discussion section). The gene networks of upregulated genes (red) and downregulated genes (green) also indicate their key upstream regulators (yellow). Solid arrows: affecting gene expression.

Journal: Biomedicines

Article Title: DSCAM-AS1 Long Non-Coding RNA Exerts Oncogenic Functions in Endometrial Adenocarcinoma via Activation of a Tumor-Promoting Transcriptome Profile

doi: 10.3390/biomedicines10071727

Figure Lengend Snippet: Networks of genes regulated upon silencing of DSCAM-AS1 in HEC-1B and RL95-2 cells as assessed by Affymetrix GeneChip and subsequent pathway analyses using Ingenuity Pathway Analysis (IPA) software (Qiagen Bioinformatics). Knockdown was less efficient in RL95-2 cells due to its positive ERα status (see Discussion section). The gene networks of upregulated genes (red) and downregulated genes (green) also indicate their key upstream regulators (yellow). Solid arrows: affecting gene expression.

Article Snippet: For data analysis, by means of the RMA algorithm in the Affymetrix GeneChip Expression Console Software, summarized probe signals were created.

Techniques: Software, Expressing